About Sanford Health
Sanford Health Nursing Jobs: Rural Nursing, Redefined at Scale
Rural nursing has a reputation problem. The assumption is fewer resources, limited specialties, and professional isolation. Sanford Health — the largest rural health system in the United States — has spent recent years systematically dismantling that narrative. With 58 hospitals and 289 clinic locations across South Dakota, North Dakota, Minnesota, Iowa, Wisconsin, Wyoming, and Michigan's Upper Peninsula, Sanford serves over 2 million patients across 320,000 square miles. If you're considering Sanford Health nursing jobs, you're looking at a system where rural doesn't mean small and remote doesn't mean disconnected.
The $350 Million Bet on Virtual Care
In 2021, philanthropist Denny Sanford gifted $350 million to transform virtual care delivery. That investment became tangible in late 2024 when Sanford opened its 60,000-square-foot Virtual Care Center in Sioux Falls — a purpose-built hub for telemedicine, hospital-at-home programs, remote monitoring, and AI-focused innovation. The system now delivers virtual care across nearly 80 specialties, and its virtual nursing pilot pairs remote RNs with bedside nurses for documentation, mentoring, and clinical monitoring in real time.
For nurses, this means two things. If you work in a critical-access hospital, you have specialist backup at the touch of a button — emergency-trained nurses and physicians available virtually around the clock. And virtual nursing roles are expanding, creating career paths for experienced RNs who want clinical work without relocation. Each virtual visit saves patients an average 176-mile round trip.
A System That Keeps Growing
Sanford completed three major moves in 2025: merging with Wisconsin-based Marshfield Clinic Health System, absorbing South Dakota's Prairie Lakes Healthcare System, and acquiring Lewis Drug, a 60-location pharmacy chain. The organization now employs 55,000 people, includes roughly 4,500 physicians and APPs, and runs over 1,100 active clinical trials. Fortune named Sanford one of America's Most Innovative Companies three consecutive years (2023–2025), and both its Sioux Falls and Fargo medical centers made Becker's 100 Great Hospitals list for 2025.
This growth expands the internal job market. Solutions by Sanford, the system's internal travel nursing program, lets nurses take assignments across the Midwest without leaving the organization. A separate Workforce Pool supports flexible long-term care travel nursing with the option to return home each night.
Magnet Recognition and New-Nurse Support
Three Sanford campuses hold Magnet designation: Sanford USD Medical Center (since 2003, five consecutive designations), Sanford Bismarck (since 2008, four consecutive), and Sanford Medical Center Fargo (newly designated in 2025). The Nurse Residency Program carries ANCC accreditation with distinction and automatically enrolls every new graduate RN, providing structured mentorship and patient-safety training during the transition to practice. Sanford is also an ANCC-accredited provider of Nursing Continuing Professional Development, offering free or reduced-cost CE across specialties.
Compensation and Benefits
Sanford has delivered annual salary increases for over 20 consecutive years, plus a yearly holiday bonus. Benefits include comprehensive health insurance, a 401(k) with up to 5% employer match, no-cost disability and life insurance for eligible employees, dental and vision plans, and PTO that accrues at increasing rates with tenure. In 2025, Sanford expanded its family-building benefit covering adoption, fertility, and surrogacy, and increased employee counseling to six sessions per incident.
Where the Jobs Are
Sanford Health nursing jobs span the 384-bed Fargo Medical Center — North Dakota's only Level I adult trauma center — to 25-bed critical-access hospitals in communities counted in hundreds. Sanford Children's Hospital in Sioux Falls is the region's only verified pediatric trauma center, and the Good Samaritan Society affiliate adds 145 senior care communities. Whether you want a trauma floor, a virtual nursing desk, or a clinic where you know every patient by name, start on RegisteredNurse.jobs.
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